產(chǎn)品名稱 |
Y-156 |
商品貨號 |
B219849 |
Designations |
Y-156 |
Species |
Homo sapiens, human |
Vector |
Construct size (kb): 7.199999809265137 |
Insert |
DNA: genomic Insert lengths(kb): 4.400000095367432 Tissue: 49,XXXXY cell line Gene product: DNA Segment [DYZ*2] |
Insert Size (kb) |
4.400 |
Biosafety Level |
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country. |
Shipping Information |
Distributed: DNA (dried). Rehydrate with TE. (amount: 2 ug) |
Comments |
Restriction digests of the clone give the following sizes (kb): AvaI--2.7, 2.4, 2.1; BamHI--7.2; EcoRI--4.4, 2.8; NotI--uncut; HindIII--4.4, 2.8. This probe detects a Y-specific 4.4 kb HindIII fragment which has about 10 copies in normal males. It also detects 6 fainter Y-specific bands ranging from 2 to 15 kb. The copy number of the 4.4 kb fragment may be reduced in gonadal dysgenesis. |
References |
Muller U, et al. Moderately repeated DNA sequences specific for the short arm of the human Y chromosome are present in XX males and reduced in copy number in an XY female. Nucleic Acids Res. 14: 1325-1340, 1986. PubMed: 3951989
Gaunt SJ. Mapping of testis-determining locus on Yp by the molecular genetic analysis of XX males and XY females. Development 101: 51-58, 1987. PubMed: 88211484
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