Restriction digests of the clone give the following sizes (kb): EcoRI/HindIII--2.5, 1.9, 0.6; AccI--5.0; BamHI--5.0; HindIII--5.0; consistent with deposited DNA. Codominant segregation was observed in 36 three-generation families. RFLPs were observed after competitive hybridization with total human DNA. Enzyme(s) not detecting polymorphism: TaqI and PstI. |