Biological understanding of top genetic alterations across tumor types
Validation and characterization of potential cancer driver genes
Functional profiling and molecular profiling of subtype-specific cancer cell lines
Testing small molecules or biologics for cancer drug development
Type Strain
no
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Comments
A panel of 17 triple-negative breast tumor cell lines sharing a mesenchymal-like or luminal morphology. See J Clinical Inv (2011) 121(7):2750-2767 for more information.
RefLehmann BD, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J. Clin. Invest. 121: 2750-2767, 2011. PubMed: 21633166