Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--3.5, 2.6; PstI--6.1; SacI--3.2, 2.7; BglI--5.0, 1.1; PvuII--3.7, 2.3. D15S24 is also polymorphic with the following enzymes: MspI, BanII, BglI, BglII, BstEII, SacI, PstI, EcoRV, PvuII, ApaI, DraI, KpnI, and BstNI. Codominant segregation shown for alleles detected with EcoRI and TaqI in two informative Caucasian families totalling 17 individuals. Not polymorphic for ScaI, XbaI in 6 unrelated individuals. |
References |
Rich DC, et al. Highly polymorphic locus D15S24 (CMW-1) maps to 15pter-q13. Nucleic Acids Res. 16: 8740, 1988. PubMed: 2901727
Cogen PH, et al. Deletion mapping of the medulloblastoma locus on chromosome 17p. Genomics 8: 279-285, 1990. PubMed: 1979050
|